When baking banana bread at 375 degrees Fahrenheit, the cooking time usually ranges between 50 to 60 minutes. However, the exact duration can vary based on factors such as the size and shape of the loaf pan, the ripeness and moisture content of the bananas, and the accuracy of your oven.To ensure that the banana bread is fully cooked, you can perform the toothpick test. Insert a toothpick into the center of the bread; if it comes out clean or with a few crumbs, it's ready.